Aldo-keto reductase family 1 member C3 isoform 1, 1-323aa, Human, E.coli (Bioactivity Validated) IBATGP3276 from IBL- America

Description

AKR1C3 also known as Aldo-keto reductase family 1 member C3 isoform 1, is a member of the aldo-keto reductase superfamily which catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9 alpha, 11 beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and differentiation. Recombinant human AKR1C3 protein was expressed in E.coli and purified by using conventional chromatography techniques

Product Specs
ItemAldo-keto reductase family 1 member C3 isoform 1, 1-323aa, Human, E.coli (Bioactivity Validated)
CompanyIBL- America
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberIBATGP3276
Quantity10 µg
ApplicationsSDS-PAGE
Concentration1 mg/ml (determined by Bradford assay)
FormatLiquid. In 20mM Tris-HCl buffer (pH 8.5) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Purity> 90% by SDS - PAGE
TypeRecombinant Protein
Molecular Weight36.8kDa (323aa)
SpeciesHuman
Source/Expression SystemE.coli
Regulatory StatusFor research use only, not for use in diagnostic procedures
NCBI Full Gene Namealdo-keto reductase family 1 member C3
NCBI Gene AliasesDD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS
Domain/Region/Terminus1-323aa
StorageCan be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles